Optical tweezers applied to a microfluidic system
نویسندگان
چکیده
منابع مشابه
A microfluidic system with optical laser tweezers to study mechanotransduction and focal adhesion recruitment.
We present a new method to locally apply mechanical tensile and compressive force on single cells based on integration of a microfluidic device with an optical laser tweezers. This system can locate a single cell within customized wells exposing a square-like membrane segment to a functionalized bead. Beads are coated with extracellular matrix (ECM) proteins of interest (e.g. fibronectin) to ac...
متن کاملMicrofluidic sorting of arbitrary cells with dynamic optical tweezers.
Optical gradient forces generated by fast steerable optical tweezers are highly effective for sorting small populations of cells in a lab-on-a-chip environment. The presented system can sort a broad range of different biological specimens by an automated optimisation of the tweezer path and velocity profile. The optimal grab positions for subsequent trap and cell displacements are estimated fro...
متن کاملOptical Tweezers
An optical tweezers apparatus uses a tightly focused laser to generate a trapping force that can capture and move small particles under a microscope. Because it can precisely and non-destructively manipulate objects such as individual cells and their internal components, the optical tweezers is extremely useful in biological physics research. In this experiment the student will use optical twee...
متن کاملOptical Tweezers
An optical tweezers apparatus uses a tightly focused laser to generate a trapping force that can capture and move small particles under a microscope. Because it can precisely and nondestructively manipulate objects such as individual cells and their internal components, the optical tweezers is extremely useful in biological physics research. In this experiment you will use optical tweezers to t...
متن کاملOptical Tweezers
H€ansch TW, Picqué N. Frequency combs. In: Tr€ager F, editor. Handbook of lasers and optics. 2nd ed. Springer Berlin: Heidelberg; (2012). Ideguchi T et al. Adaptive real-time dual comb spectroscopy. arXiv:1201.4177 (2012). Jacquet, P., et al. Frequency comb Fourier transform spectroscopy with kHz optical resolution. In: Fourier transform spectroscopy. Washington, DC: Optical Society of America;...
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ژورنال
عنوان ژورنال: Lab Chip
سال: 2004
ISSN: 1473-0197,1473-0189
DOI: 10.1039/b307960k